Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043536 | 0.82 | KMT2A (0.38) | — | |
| SCHEMBL11345030 | 0.76 | APOBEC3G (0.45) | — | |
| SCHEMBL10661809 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL16295402 | 0.76 | NNMT (0.33) | — | |
| SCHEMBL11342191 | 0.73 | TDP1 (0.36) | — | |
| SCHEMBL7849449 | 0.72 | SMN1; SMN2 (0.51) | KEAP1 | |
| SCHEMBL5387281 | 0.72 | KIF11 (0.34) | — | |
| SCHEMBL6599939 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL7839475 | 0.71 | KEAP1 (0.39) | KEAP1 | |
| SCHEMBL2536094 | 0.71 | KCNE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934940-A1 | CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF | Japan Tobacco Inc. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5807850-A | Therapeutic agent for osteoporosis and triazepine compound | JAPAN TOBACCO, INC. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0792880-A1 | OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND | Japan Tobacco Inc. (JP) | 1997-09-03 | — | — | EP | disclosed |