Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174291 | 0.82 | NPC1 (0.42) | ALDH1A1HDAC8LMNA | |
| SCHEMBL11351505 | 0.79 | HTR2C (0.36) | ALDH1A1HDAC8LMNAGAAIDO1 | |
| SCHEMBL11348982 | 0.77 | IDO1 (0.35) | MAPTHDAC8LMNABACE1TP53 | |
| SCHEMBL11346420 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1MAPTPOLBLMNAHPGD | |
| SCHEMBL11349490 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBLMNA | |
| Dimethylamine SCHEMBL11347087 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTHDAC8LMNA | |
| SCHEMBL8761415 | 0.76 | LMNA (0.42) | ALDH1A1MAPTLMNAHPGDIDO1 | |
| SCHEMBL11351610 | 0.76 | L3MBTL1 (0.45) | ALDH1A1MAPTPOLBLMNAGAA | |
| SCHEMBL11180716 | 0.76 | MAOA (0.39) | ALDH1A1LMNAGAAHPGDIDO1 | |
| SCHEMBL11178221 | 0.76 | L3MBTL1 (0.47) | ALDH1A1MAPTPOLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |