Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347391 | 0.86 | L3MBTL1 (0.35) | L3MBTL1MAPTTSHRMAPK1RAB9A | |
| SCHEMBL11351610 | 0.83 | L3MBTL1 (0.45) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11180716 | 0.83 | MAOA (0.39) | L3MBTL1RAB9ANPC1TDP1MEN1 | |
| SCHEMBL11352659 | 0.83 | CA2 (0.36) | L3MBTL1SMN1; SMN2GAALMNA | |
| SCHEMBL11174291 | 0.82 | NPC1 (0.42) | L3MBTL1MAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11351617 | 0.82 | RAB9A (0.41) | L3MBTL1RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL11348606 | 0.82 | APP (0.46) | MAPTMAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11346420 | 0.81 | SMN1; SMN2 (0.42) | L3MBTL1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11180204 | 0.79 | ALDH1A1 (0.35) | L3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL8761415 | 0.76 | LMNA (0.42) | L3MBTL1MAPTMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |