Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 10/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760347 | 0.84 | CYP2C9 (0.68) | CYP2C9TTRCYP3A4ALDH1A1MAPT | |
| SCHEMBL11319388 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL18415631 | 0.80 | PTPN1 (0.61) | CYP2C9TTR | |
| SCHEMBL18407419 | 0.79 | CYP2C9 (0.58) | CYP2C9TTR | |
| SCHEMBL4801386 | 0.77 | NQO1 (0.49) | CYP2C9TTRKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL11360558 | 0.77 | KDM4E (0.53) | CYP2C9TTRKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL9348216 | 0.76 | CYP2C9 (0.54) | CYP2C9TTRKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL7030133 | 0.76 | KCNH2 (0.48) | CYP2C9KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9760981 | 0.76 | CYP2C9 (0.66) | CYP2C9TTRKDM4ECYP3A4ALDH1A1 | |
| Xanthone SCHEMBL27718443 | 0.76 | MAOA (0.62) | TTRKDM4ECYP3A4ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |