Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334220 | 0.96 | MEN1 (0.44) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11447020 | 0.87 | OPRD1 (0.42) | MEN1KMT2ASIGMAR1OPRM1OPRD1 | |
| SCHEMBL11446906 | 0.86 | SIGMAR1 (0.39) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11437822 | 0.86 | MEN1 (0.42) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11447557 | 0.86 | OPRM1 (0.50) | MEN1KMT2ASIGMAR1CHRM3OPRM1 | |
| SCHEMBL11465431 | 0.85 | HPGD (0.39) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11347007 | 0.83 | SIGMAR1 (0.43) | MEN1KMT2ASIGMAR1OPRM1OPRD1 | |
| SCHEMBL11331580 | 0.83 | SIGMAR1 (0.41) | MEN1KMT2ASIGMAR1CHRM2CHRM3 | |
| SCHEMBL11447250 | 0.83 | OPRM1 (0.45) | SIGMAR1CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL11465462 | 0.83 | OPRM1 (0.45) | SIGMAR1CHRM3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | claimed |