Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549159 | 0.74 | TP53 (0.46) | TSHRMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL3037947 | 0.74 | SIGMAR1 (0.72) | TSHRKMT2APKMSIGMAR1ALDH1A1 | |
| SCHEMBL11347486 | 0.74 | SIGMAR1 (0.72) | TSHRKMT2APKMSIGMAR1ALDH1A1 | |
| SCHEMBL7329630 | 0.71 | SIGMAR1 (0.81) | TSHRSIGMAR1 | |
| SCHEMBL9318596 | 0.71 | TP53 (0.42) | TSHRSIGMAR1SLC6A3ALDH1A1LMNA | |
| SCHEMBL17965484 | 0.70 | CA1 (0.42) | SLC18A3TSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL368873 | 0.69 | ESR2 (0.38) | TSHRSIGMAR1 | |
| SCHEMBL7248849 | 0.69 | CCR3 (0.73) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL251994 | 0.69 | CA1 (0.41) | SLC18A3TSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL368538 | 0.69 | CHKA (0.40) | TSHRSIGMAR1SLC6A3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243805-A | 3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1981-01-06 | — | — | US | disclosed |