Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496948 | 0.94 | JAK2 (0.45) | JAK2JAK1MAPTDCAF1MAPK1 | |
| SCHEMBL1134824 | 0.87 | CHRM3 (0.51) | JAK2JAK1DCAF1CHRM3 | |
| SCHEMBL302468 | 0.87 | JAK2 (0.48) | JAK2JAK1MAPTDCAF1CHRM3 | |
| SCHEMBL29451182 | 0.84 | TP53 (0.40) | JAK2JAK1MAPTMAPK1NTRK1 | |
| SCHEMBL16594331 | 0.84 | TP53 (0.40) | JAK2JAK1MAPTMAPK1NTRK1 | |
| SCHEMBL28939590 | 0.83 | JAK2 (0.44) | JAK2JAK1MAPTDCAF1MAPK1 | |
| SCHEMBL1144969 | 0.82 | CHRM3 (0.43) | MAPK1CHRM3CSNK1DCSNK1ETP53 | |
| SCHEMBL1136276 | 0.82 | CHRM3 (0.51) | CHRM3 | |
| SCHEMBL1767591 | 0.81 | CHRM3 (0.46) | JAK2JAK1MAPTNTRK1CHRM3 | |
| SCHEMBL303047 | 0.80 | CHRM3 (0.51) | MAPK1CHRM3CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233000-B1 | Post-harvest treatment | BAYER IP GMBH (DE) | 2016-07-13 | — | — | EP | claimed |
| EP-2258178-B1 | Use of alkykl carboxylic acid amides as penetration promoters | BAYER CROPSCIENCE AG (DE) | 2012-07-04 | — | — | EP | claimed |
| US-9743674-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2016-10-13 | — | — | US | disclosed |
| US-20130303376-A1 | METHODS OF IMPROVING PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2013-11-14 | — | — | US | disclosed |
| EP-1796468-B1 | Synergistic fungicidal active substance combinations containing spiroxamine, prothioconazole and bixafen | BAYER CROPSCIENCE AG (DE) | 2011-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | O60361, SPOUT1, FBL | JAK2 3988/4885JAK1 2790/4885MAPT 3739/4885 |
| US-20130303376-A1 | METHODS OF IMPROVING PLANT GROWTH | MYCBP, MYB, MRPL37 | JAK2 3148/4885JAK1 3112/4885MAPT 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.