Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343752 | 0.87 | ELANE (0.46) | KMT2AELANETSHRPOLBSMN1; SMN2 | |
| SCHEMBL11353850 | 0.82 | ELANE (0.51) | ELANETSHRPOLBKDM4ERECQL | |
| SCHEMBL11353849 | 0.81 | ALDH1A1 (0.64) | KMT2ATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11344233 | 0.81 | THRB (0.56) | KMT2ATSHRPOLBKDM4ERECQL | |
| SCHEMBL27972749 | 0.80 | KMT2A (0.57) | KMT2ATSHRPOLBKDM4ERECQL | |
| SCHEMBL11353847 | 0.79 | NR3C2 (0.45) | ELANEPOLBALDH1A1 | |
| SCHEMBL2703931 | 0.77 | ELANE (0.57) | KMT2AELANEPOLBATMHTT | |
| SCHEMBL17791332 | 0.77 | ELANE (0.57) | KMT2AELANEPOLBSMN1; SMN2ATM | |
| SCHEMBL3255431 | 0.77 | PGR (0.50) | KMT2AELANEKDM4ERECQLSMN1; SMN2 | |
| SCHEMBL56436 | 0.77 | ELANE (0.69) | KMT2AELANEPOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259469-A | DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY | EASTMAN KODAK COMPANY (US) | 1981-03-31 | — | — | US | disclosed |