Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972749 | 0.81 | KMT2A (0.57) | KMT2ATSHRPOLBKDM4ERECQL | |
| SCHEMBL11348702 | 0.81 | KMT2A (0.53) | KMT2ATSHRPOLBKDM4ERECQL | |
| SCHEMBL9326040 | 0.76 | PGR (0.51) | THRBKDM4ERECQLSMN1; SMN2NPC1 | |
| SCHEMBL4595847 | 0.75 | THRB (0.74) | THRBKMT2ATSHRPOLBSMN1; SMN2 | |
| SCHEMBL1530297 | 0.75 | CNR2 (0.68) | KMT2ATSHRSMN1; SMN2CNR2HTT | |
| SCHEMBL99981 | 0.75 | THRB (0.68) | THRBKMT2ATSHRPOLB | |
| SCHEMBL17791334 | 0.75 | THRB (0.79) | THRBTSHRALDH1A1 | |
| SCHEMBL2580708 | 0.75 | THRB (0.68) | THRBKMT2APOLB | |
| SCHEMBL7230378 | 0.75 | KMT2A (0.65) | KMT2ATSHRPOLBKDM4ERECQL | |
| SCHEMBL2587522 | 0.74 | THRB (0.64) | THRBKMT2ATSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259469-A | DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY | EASTMAN KODAK COMPANY (US) | 1981-03-31 | — | — | US | disclosed |