Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19187750 | 0.77 | LMNA (0.37) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL9208767 | 0.76 | RAB9A (0.46) | SMN1; SMN2LMNAPOLBALDH1A1CYP1A2 | |
| SCHEMBL3110927 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL27773929 | 0.76 | CASP3 (0.40) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL11348757 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL20565261 | 0.75 | POLB (0.47) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL805420 | 0.73 | — | — | |
| SCHEMBL1805165 | 0.72 | L3MBTL1 (0.57) | SMN1; SMN2LMNACASP3SENP8SENP7 | |
| SCHEMBL7887713 | 0.71 | CYP1A2 (0.53) | SMN1; SMN2LMNATDP1ALDH1A1CYP1A2 | |
| SCHEMBL1843260 | 0.71 | LMNA (0.42) | SMN1; SMN2LMNACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984082-A1 | NOVEL TRIAZOLE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167010-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-10-16 | — | — | WO | disclosed |
| EP-0002678-B1 | AZOLYLALKYL-PYRIDINYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |