Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110927 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL20565261 | 0.80 | POLB (0.47) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL29431315 | 0.79 | CYP1A2 (0.62) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL950737 | 0.79 | CYP1A2 (0.62) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL2178576 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL4126633 | 0.77 | P2RX7 (0.45) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL16540510 | 0.77 | P2RX7 (0.51) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL18751691 | 0.76 | HSD11B1 (0.47) | SMN1; SMN2POLBHTTALDH1A1RAB9A | |
| SCHEMBL11348793 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAP2RX7CASP3SENP8 | |
| SCHEMBL8446184 | 0.75 | ALDH1A1 (0.50) | MAPTNPC1ALDH1A1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984082-B1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| EP-2984082-B1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-9668481-B2 | Triazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9668481-B2 | Triazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9668481-B2 | Triazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-06 | — | — | US | disclosed |
| US-20160050928-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| EP-2984082-A1 | NOVEL TRIAZOLE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167010-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014167010-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-10-16 | — | — | WO | disclosed |
| EP-0002678-B1 | AZOLYLALKYL-PYRIDINYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050928-A1 | NOVEL TRIAZOLE DERIVATIVES | ERG28, CYP51A1, SBK3 | SMN1; SMN2 4875/4885LMNA 4316/4885P2RX7 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.