SCHEMBL11348983

SCHEMBL11348983

CC(C)C[Si](Cl)(Cl)CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
SIGMAR1 Q99720 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8505708 0.84 AOC3 (0.42) AOC3TDP1
SCHEMBL11414579 0.83 AOC3 (0.43) AOC3TDP1HPGDKMT2AALDH1A1
SCHEMBL28791396 0.81 CA2 (0.45) TDP1KMT2AALDH1A1SIGMAR1CYP2D6
SCHEMBL1030793 0.81 TDP1 (0.52) AOC3TDP1HPGDALDH1A1SIGMAR1
SCHEMBL11213202 0.79 ALDH1A1 (0.40) AOC3TDP1ALDH1A1NPC1RAB9A
SCHEMBL11341539 0.78 TDP1 (0.44) AOC3TDP1HPGDALDH1A1NPC1
SCHEMBL11345056 0.76 TDP1 (0.43) AOC3TDP1HPGDALDH1A1SIGMAR1
SCHEMBL11414972 0.76 SIGMAR1 (0.43) AOC3TDP1HPGDKMT2AALDH1A1
SCHEMBL523575 0.76 TDP1 (0.43) AOC3TDP1HPGDKMT2AALDH1A1
SCHEMBL4086275 0.75 TDP1 (0.46) AOC3TDP1HPGDKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000614-B1 PRODUCTION OF DICHLOROSILANE DERIVATIVES Chisso Corporation (JP) 1981-11-25 EP disclosed
US-4242272-A Substituted phenethyldichlorosilanes and method for producing same CHISSO CORPORATION (JP) 1980-12-30 US disclosed
EP-0000614-A1 Production of dichlorosilane derivatives Chisso Corporation (JP) 1979-02-07 EP disclosed