Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523575 | 0.83 | TDP1 (0.43) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL11348983 | 0.76 | AOC3 (0.41) | SIGMAR1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL523393 | 0.76 | TDP1 (0.48) | TAAR1SLC6A2MAOACYP2A6TDP1 | |
| SCHEMBL523595 | 0.76 | TDP1 (0.48) | TAAR1SLC6A2MAOACYP2A6TDP1 | |
| SCHEMBL5804199 | 0.75 | TDP1 (0.48) | SIGMAR1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL208903 | 0.75 | TDP1 (0.52) | SIGMAR1TAAR1SLC6A2MAOACYP2A6 | |
| SCHEMBL1030793 | 0.75 | TDP1 (0.52) | SIGMAR1TAAR1SLC6A2MAOACYP2A6 | |
| SCHEMBL1482295 | 0.75 | TDP1 (0.52) | SIGMAR1TAAR1SLC6A2MAOACYP2A6 | |
| SCHEMBL11414579 | 0.75 | AOC3 (0.43) | SIGMAR1TDP1CYP2C9CYP2C19KMT2A | |
| SCHEMBL6532094 | 0.73 | TDP1 (0.50) | SIGMAR1TAAR1SLC6A2MAOACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242272-A | Substituted phenethyldichlorosilanes and method for producing same | CHISSO CORPORATION (JP) | 1980-12-30 | — | — | US | disclosed |
| EP-0000614-A1 | Production of dichlorosilane derivatives | Chisso Corporation (JP) | 1979-02-07 | — | — | EP | disclosed |