Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.43 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801469 | 0.81 | SLC13A5 (0.43) | SLC13A5SLC13A2SLC13A3LMNAALDH1A1 | |
| SCHEMBL27465508 | 0.80 | NOS3 (0.41) | SLC13A5SLC13A2SLC13A3LMNAALDH1A1 | |
| SCHEMBL12093547 | 0.78 | SLC13A5 (0.51) | SLC13A5SLC13A2SLC13A3KDM4EMAPT | |
| SCHEMBL25168223 | 0.77 | LMNA (0.37) | SLC13A5SLC13A2SLC13A3LMNAALDH1A1 | |
| SCHEMBL19819860 | 0.75 | SLC13A5 (0.42) | SLC13A5SLC13A2SLC13A3ALDH1A1HPGD | |
| SCHEMBL27483530 | 0.75 | PKM (0.37) | LMNAALDH1A1GLAF2HPGD | |
| SCHEMBL8150962 | 0.73 | SLC13A5 (0.37) | SLC13A5SLC13A2SLC13A3MAPTMAPK1 | |
| SCHEMBL3083354 | 0.72 | LMNA (0.47) | LMNAALDH1A1GLAHPGDKDM4E | |
| SCHEMBL11447584 | 0.71 | GLA (0.47) | LMNAALDH1A1GLAF2HPGD | |
| SCHEMBL814188 | 0.70 | KDM4E (0.42) | SLC13A5LMNAKDM4EMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958946-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |