Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363587 | 0.89 | NR1H3 (0.46) | ALOX5EPHX2NR1H3RORCADRB2 | |
| SCHEMBL1809776 | 0.85 | RORC (0.60) | ALOX5EPHX2NR1H3RORCKCNT1 | |
| SCHEMBL16494456 | 0.76 | ALOX5 (0.51) | ALOX5EPHX2ADRB2ADRB1ADRB3 | |
| SCHEMBL26915821 | 0.76 | MAPT (0.49) | NR1H3ADRB2ADRB1ADRB3ACHE | |
| SCHEMBL29875634 | 0.75 | ALDH1A1 (0.66) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL29558 | 0.75 | ALDH1A1 (0.66) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL7710166 | 0.75 | ALOX5 (0.53) | ALOX5EPHX2ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL16495178 | 0.75 | ALOX5 (0.50) | ALOX5EPHX2ADRB2ADRB1ADRB3 | |
| SCHEMBL16625623 | 0.74 | HDAC1 (0.49) | ALOX5EPHX2NR1H3RORCHDAC1 | |
| SCHEMBL7338251 | 0.74 | HDAC1 (0.54) | ALOX5EPHX2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251659-A | Polyfluorohydroxyisopropyl-heterocyclic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-17 | — | — | US | disclosed |