Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16558083 | 0.92 | HDAC1 (0.59) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL1809776 | 0.84 | RORC (0.60) | RORCNR1H3ALOX5EPHX2 | |
| SCHEMBL15525689 | 0.82 | NR1H3 (0.44) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL15528373 | 0.82 | HDAC6 (0.54) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL15528711 | 0.79 | ALOX5 (0.53) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL15529401 | 0.79 | HDAC6 (0.45) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL15603578 | 0.79 | RORC (0.42) | HDAC1HDAC6HDAC8RORCNR1H3 | |
| SCHEMBL15529339 | 0.78 | HDAC6 (0.60) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3850387 | 0.78 | ALDH1A1 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL16558086 | 0.78 | HDAC6 (0.46) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447069-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | RORB, RORA, RORC | HDAC1 460/4885HDAC6 381/4885HDAC3 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.