SCHEMBL11352154

SCHEMBL11352154

OCCOCCOc1[c]cccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
ALDH1A1 P00352 7/20 0.38
RECQL P46063 1/20 0.38
APP P05067 5/20 0.38
MAPK1 P28482 3/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
USP2 O75604 1/20 0.36
CYP3A4 P08684 1/20 0.36
CASP1 P29466 1/20 0.36
SLCO1B3 Q9NPD5 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
PTK2B Q14289 1/20 0.35
KDM4E B2RXH2 4/20 0.35
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348920 0.89 ALDH1A1 (0.48) KMT2AMEN1ALDH1A1RECQLSMN1; SMN2
SCHEMBL29265292 0.86 APP (0.38) KMT2AALDH1A1APPMAPK1LMNA
SCHEMBL6238419 0.84 JAK2 (0.33) ALDH1A1RECQLMAPK1LMNASMN1; SMN2
SCHEMBL2762966 0.83 ALDH1A1 (0.38) KMT2AMEN1ALDH1A1RECQLKDM4E
SCHEMBL1416274 0.83 SMN1; SMN2 (0.46) KMT2AMEN1ALDH1A1TSHRLMNA
SCHEMBL8196472 0.82 NPC1 (0.47) KMT2AALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL7779040 0.82 L3MBTL1 (0.37) KMT2AMEN1ALDH1A1RECQLMAPK1
SCHEMBL7281298 0.82 L3MBTL1 (0.37) KMT2AALDH1A1MAPK1LMNASMN1; SMN2
SCHEMBL1416377 0.81 ALDH1A1 (0.35) KMT2AMEN1ALDH1A1LMNASMN1; SMN2
SCHEMBL1416259 0.81 SMN1; SMN2 (0.47) ALDH1A1TSHRLMNASMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4248997-A FROM A CYCLOPENTADIENE TYPE COMPOUND WHICH HAS BEEN REACTED WITH AN UNSATURATED POLYOL AND SELECTIVELY HYDROGENATING THE DOUBLE BOND TOYO INK MANUFACTURING CO., LTD. (JP) 1981-02-03 US disclosed
US-4177122-A ETHERIFICATION WITH AN ALKYLENE OXIDE FOLLOWED BY ESTERIFICATION WITH AN UNSATURATED CARBOXYLIC ACID TOYO INK MANUFACTURING CO., LTD. (JP) 1979-12-04 US disclosed