Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350348 | 0.86 | ALDH1A1 (0.59) | NCF1ALDH1A1KDM4ESMN1; SMN2ACHE | |
| SCHEMBL7923899 | 0.82 | ALDH1A1 (0.43) | NOS3NOS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11355252 | 0.81 | NR4A2 (0.50) | NCF1NOS3NOS1ACHETLR7 | |
| SCHEMBL11349234 | 0.78 | NCF1 (0.56) | NCF1NOS3NOS1ALDH1A1KDM4E | |
| SCHEMBL8349539 | 0.78 | KDM4E (0.78) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL13409362 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2ACHEMPO | |
| SCHEMBL15283397 | 0.77 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL8301655 | 0.76 | BACE1 (0.56) | NCF1NOS3NOS1ALDH1A1KDM4E | |
| SCHEMBL12762533 | 0.76 | HTR1A (0.52) | CYP3A4TLR8 | |
| SCHEMBL1166339 | 0.75 | NCF1 (0.51) | NCF1NOS3NOS1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279912-A | ANTIALLERGENS, BRONCHODILATORS | ROUSSEL UCLAF (FR) | 1981-07-21 | — | — | US | disclosed |