Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354583 | 0.82 | NCF1 (0.46) | ALDH1A1KDM4ESMN1; SMN2NOS3NOS1 | |
| SCHEMBL13409362 | 0.75 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2MPOACHE | |
| SCHEMBL8349539 | 0.75 | KDM4E (0.78) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL12762533 | 0.73 | HTR1A (0.52) | FERMT2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL13409360 | 0.72 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1GAA | |
| SCHEMBL13757499 | 0.71 | PDE10A (0.45) | ALDH1A1KDM4ESMN1; SMN2HTR1AADRA1D | |
| SCHEMBL15283397 | 0.71 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2ADRA1AMEN1 | |
| SCHEMBL13966270 | 0.70 | MAPT (0.55) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL13757634 | 0.70 | KDM4E (0.49) | ALDH1A1KDM4ESMN1; SMN2HTR1AADRA1D | |
| SCHEMBL23283481 | 0.70 | ACHE (0.46) | ALDH1A1KDM4ESMN1; SMN2FERMT2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267917-A1 | N-FUNCTIONALIZED AMIDES AS HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267917-A1 | N-FUNCTIONALIZED AMIDES AS HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, HPN, SPINT2 | ALDH1A1 628/4885KDM4E 1232/4885SMN1; SMN2 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.