Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273179 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NPSR1MPO | |
| SCHEMBL11354583 | 0.78 | NCF1 (0.46) | KDM4EALDH1A1SMN1; SMN2NPSR1MPO | |
| SCHEMBL1536620 | 0.78 | MPO (0.47) | KDM4EALDH1A1SMN1; SMN2NPSR1MPO | |
| SCHEMBL8349539 | 0.76 | KDM4E (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL7923899 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2NPSR1MPO | |
| SCHEMBL13409360 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL13757634 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL12762533 | 0.72 | HTR1A (0.52) | — | |
| SCHEMBL3427491 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2ACHEHPGD | |
| SCHEMBL13757499 | 0.71 | PDE10A (0.45) | KDM4EALDH1A1SMN1; SMN2NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |