Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353888 | 0.83 | THRB (0.34) | PTGS2L3MBTL1MAPT | |
| SCHEMBL11358154 | 0.81 | PTGS2 (0.35) | PTGS2TAAR1DHFRL3MBTL1HTR2A | |
| SCHEMBL11388917 | 0.81 | PTGS2 (0.35) | PTGS2TAAR1DHFRL3MBTL1HTR2A | |
| SCHEMBL21547572 | 0.78 | TAAR1 (0.40) | PTGS2TAAR1DHFRL3MBTL1HTR2A | |
| SCHEMBL11345628 | 0.76 | GABRA1 (0.41) | DHFR | |
| SCHEMBL11365754 | 0.76 | ALDH1A1 (0.37) | DHFR | |
| SCHEMBL11355693 | 0.75 | IMPDH2 (0.35) | PTGS2TAAR1DHFR | |
| SCHEMBL12325395 | 0.72 | PTGS2 (0.44) | PTGS2TAAR1DHFRHTR2AMAPT | |
| SCHEMBL11354014 | 0.72 | PTGS2 (0.39) | PTGS2DHFRHTR2A | |
| SCHEMBL2945602 | 0.70 | ALDH1A1 (0.48) | PTGS2TAAR1HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |