SCHEMBL1136007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136119	0.91	MAOB (0.40)	METKDRAXLIDO1PRKAB2
	SCHEMBL2432859	0.90	ADORA3 (0.43)	ADORA3METKDRAXLIDO1
	SCHEMBL2493104	0.90	MET (0.41)	METKDRAXLIDO1PRKAB2
	SCHEMBL1136039	0.90	MET (0.39)	METKDRAXLIDO1PRKAB2
	SCHEMBL2430280	0.89	ADORA3 (0.42)	ADORA3IDO1ALDH1A1KDM4ECYP3A4
	SCHEMBL1136187	0.89	ALDH1A1 (0.42)	METKDRAXLIDO1PRKAB2
	SCHEMBL1136262	0.89	MET (0.43)	METKDRAXLIDO1PRKAB2
	SCHEMBL1136103	0.88	MET (0.40)	METKDRAXLIDO1PRKAB2
	SCHEMBL2584922	0.87	PTGDR2 (0.50)	METKDRAXLPRKAB2PRKAG1
	SCHEMBL1136151	0.86	ADORA3 (0.44)	ADORA3METKDRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.