SCHEMBL1136023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136191	0.86	MET (0.38)	TDP1BRD4
	SCHEMBL1136059	0.86	MET (0.40)	TDP1BRD4
	SCHEMBL1136007	0.80	ADORA3 (0.40)	ALDH1A1LMNAHPGDSMN1; SMN2RAB9A
	SCHEMBL2493104	0.79	MET (0.41)	ALDH1A1LMNASMN1; SMN2RAB9AHSD17B10
	SCHEMBL1136039	0.79	MET (0.39)	ALDH1A1LMNASMN1; SMN2RAB9AHSD17B10
	SCHEMBL1136187	0.79	ALDH1A1 (0.42)	ALDH1A1LMNASMN1; SMN2RAB9AHSD17B10
	SCHEMBL1136283	0.79	KDR (0.38)	—
	SCHEMBL1136119	0.78	MAOB (0.40)	ALDH1A1RAB9AHSD17B10KDM4EGAA
	SCHEMBL1136262	0.78	MET (0.43)	ALDH1A1RAB9AHSD17B10KDM4ENPC1
	SCHEMBL1136103	0.78	MET (0.40)	ALDH1A1LMNASMN1; SMN2RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.