Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.39 |
| ▸ | CHRNG | P07510 | 3/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRND | Q07001 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155345 | 0.87 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL28323043 | 0.83 | SLC6A3 (0.50) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL27681431 | 0.83 | SLC6A4 (0.54) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL1154800 | 0.81 | SLC6A4 (0.57) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL652461 | 0.79 | DRD2 (0.62) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3639977 | 0.79 | OPRL1 (0.52) | OPRM1OPRD1OPRK1OPRL1SLC6A3 | |
| SCHEMBL11796632 | 0.77 | KCNA3 (0.48) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL216848 | 0.77 | DRD2 (0.60) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL42581 | 0.77 | OPRL1 (0.52) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11560742 | 0.76 | OPRD1 (0.52) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252804-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | METABIO-JOULLIE (FR) | 1981-02-24 | — | — | US | disclosed |