Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371323 | 0.86 | NPC1 (0.50) | NPC1RAB9ALMNATP53TSHR | |
| SCHEMBL11373235 | 0.84 | RAB9A (0.57) | NPC1RAB9ALMNAPOLBTP53 | |
| SCHEMBL11380905 | 0.80 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBTSHR | |
| SCHEMBL22945007 | 0.79 | ALDH1A1 (0.59) | NPC1RAB9ALMNAPOLBTSHR | |
| SCHEMBL23294109 | 0.78 | POLB (0.42) | NPC1RAB9ALMNAPOLBTP53 | |
| SCHEMBL11378240 | 0.78 | ALDH1A1 (0.51) | NPC1RAB9ALMNATSHRALDH1A1 | |
| SCHEMBL11381035 | 0.77 | LMNA (0.37) | NPC1RAB9ALMNAPOLBTSHR | |
| SCHEMBL22497308 | 0.76 | LMNA (0.43) | NPC1RAB9ALMNAPOLBTP53 | |
| SCHEMBL22497309 | 0.76 | LMNA (0.43) | NPC1RAB9ALMNAPOLBTP53 | |
| SCHEMBL11372859 | 0.75 | ALDH1A1 (0.38) | TSHRALDH1A1KMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |