SCHEMBL11367485

SCHEMBL11367485

C=CCNC(=O)Nc1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
HTT P42858 3/20 0.51
MAPT P10636 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 2/20 0.49
CA1 P00915 1/20 0.48
CA9 Q16790 1/20 0.48
ALDH1A1 P00352 4/20 0.47
TP53 P04637 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 6/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MARS1 P56192 1/20 0.45
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8701345 0.81 CFD (0.63) LMNAHTTMAPTNPC1RAB9A
SCHEMBL1649522 0.79 EPHX1 (0.59) LMNAHTTMAPTNPC1RAB9A
SCHEMBL9414768 0.78 GAA (0.61) LMNAHTTCA1CA9ALDH1A1
SCHEMBL9400389 0.78 NPC1 (0.66) LMNAHTTMAPTNPC1RAB9A
Ammonia Solution, Strong SCHEMBL11319855 0.77 EPHX1 (0.57) LMNAHTTMAPTNPC1RAB9A
SCHEMBL1951110 0.77 GAA (0.61) LMNAHTTMAPTNPC1RAB9A
SCHEMBL8693652 0.77 GAA (0.69) HTTMAPTNPC1RAB9AALDH1A1
SCHEMBL1735947 0.77 GAA (0.43) LMNAHTTMAPTNPC1RAB9A
SCHEMBL9193167 0.76 ITGB3 (0.68) LMNAHTTMAPTNPC1RAB9A
SCHEMBL7249350 0.76 MARS1 (0.53) LMNAHTTMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed