Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398081 | 0.86 | CFD (0.65) | CFDMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL8693652 | 0.84 | GAA (0.69) | MAPTALDH1A1TP53L3MBTL1HTT | |
| SCHEMBL11367485 | 0.81 | LMNA (0.51) | MAPTALDH1A1TP53L3MBTL1LMNA | |
| SCHEMBL587283 | 0.80 | ALDH1A1 (0.57) | CFDMAPTALDH1A1TP53L3MBTL1 | |
| SCHEMBL29915668 | 0.80 | ALDH1A1 (0.57) | CFDMAPTALDH1A1TP53L3MBTL1 | |
| SCHEMBL1649522 | 0.80 | EPHX1 (0.59) | MAPTALDH1A1TP53LMNAHTT | |
| SCHEMBL4749159 | 0.79 | DHODH (0.69) | CFDMAPTALDH1A1LMNAKMT2A | |
| SCHEMBL13614088 | 0.79 | GAA (0.71) | CFDMAPTALDH1A1L3MBTL1KMT2A | |
| Ammonia Solution, Strong SCHEMBL11319855 | 0.78 | EPHX1 (0.57) | MAPTALDH1A1TP53LMNAHTT | |
| SCHEMBL12476369 | 0.78 | KMT2A (0.59) | CFDMAPTALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710319-A | Process for the preparation of substituted quinazoline-2,4-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |