SCHEMBL1735947

SCHEMBL1735947

C=CC(=O)OCNC(=O)Nc1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.43
MAPT P10636 5/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 2/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 2/20 0.43
TDP1 Q9NUW8 2/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
MARS1 P56192 1/20 0.41
TP53 P04637 1/20 0.41
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
POLB P06746 1/20 0.40
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3251658 0.87 TRPV1 (0.46) GAAKMT2AMEN1KDM4EALDH1A1
SCHEMBL3243631 0.86 MARS1 (0.44) GAAMAPTLMNAHTTNPC1
SCHEMBL3255852 0.83 HDAC1 (0.51) KDM4E
SCHEMBL3252282 0.83 MARS1 (0.47) GAAMAPTLMNANPC1RAB9A
SCHEMBL3252912 0.81 GAA (0.46) GAAMAPTHTTNPC1RAB9A
SCHEMBL1735871 0.79 GAA (0.46) GAAMAPTLMNAHTTNPC1
SCHEMBL28804226 0.78 NPC1 (0.50) GAAMAPTLMNAHTTNPC1
SCHEMBL14012047 0.77 GAA (0.53) GAAMAPTLMNAHTTNPC1
SCHEMBL11367485 0.77 LMNA (0.51) GAAMAPTLMNAHTTNPC1
SCHEMBL1736740 0.77 MAOA (0.45) GAAMAPTLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-2538275-B1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2014-10-29 EP disclosed
US-20130004897-A1 METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-01-03 US disclosed
EP-2538275-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2012-12-26 EP disclosed
EP-2251195-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2011-11-16 EP disclosed
US-20110265148-A1 SYSTEM AND METHOD FOR CREATING A SECURE TRUSTED SOCIAL NETWORK TAM CHUNG MING 2011-10-27 US disclosed
EP-2251195-A1 Lithographic printing plate precursor Fujifilm Corporation (JP) 2010-11-17 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
EP-0737896-B1 Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS JP (JP) 2003-08-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed
US-5731127-A WEAR RESISTANCE, SOLVENT RESISTANCE DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-03-24 US disclosed
EP-0737896-A2 Photosensitive composition and photosensitive planographic printing plate DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-16 EP disclosed