Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524972 | 0.84 | LMNA (0.50) | CYP2D6ATMLMNAMAPK1KMT2A | |
| SCHEMBL11306349 | 0.84 | CYP2C19 (0.51) | CYP2D6FPR2NAALAD2APAF1SRC | |
| SCHEMBL11626351 | 0.82 | CYP2D6 (0.44) | CYP2D6FPR2NAALAD2APAF1SRC | |
| SCHEMBL14015971 | 0.80 | MTOR (0.52) | CYP2D6FPR2NAALAD2APAF1SRC | |
| SCHEMBL24495047 | 0.80 | MTNR1A (0.53) | FPR2NAALAD2CA1CA2 | |
| SCHEMBL8768491 | 0.79 | CYP2D6 (0.46) | CYP2D6FPR2NAALAD2APAF1SRC | |
| SCHEMBL3127115 | 0.78 | CTSS (0.46) | ATMKMT2AMEN1 | |
| SCHEMBL536302 | 0.77 | APAF1 (0.49) | CYP2D6NAALAD2APAF1SRCATM | |
| SCHEMBL306216 | 0.77 | APAF1 (0.49) | CYP2D6NAALAD2APAF1SRCATM | |
| SCHEMBL19333959 | 0.77 | APAF1 (0.49) | CYP2D6FPR2NAALAD2APAF1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000932-B1 | PRODUCTION OF N-ACYL-THIENAMYCINS | MERCK & CO. INC. (US) | 1981-10-21 | — | — | EP | claimed |