Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253495 | 0.93 | MAPT (0.69) | PTGS2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL1302256 | 0.85 | PTGS2 (0.67) | PTGS2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL27925087 | 0.83 | NPC1 (0.54) | PTGS2MAPTALDH1A1GAAMEN1 | |
| SCHEMBL28804129 | 0.81 | PLTP (0.52) | PTGS2MAPTALDH1A1GAAMEN1 | |
| SCHEMBL27925165 | 0.81 | CETP (0.50) | PTGS2MAPTALDH1A1GAAMEN1 | |
| SCHEMBL27968542 | 0.79 | RAB9A (0.59) | PTGS2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL205709 | 0.77 | MAPT (0.78) | PTGS2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL216750 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7846478 | 0.77 | PTGS2 (0.56) | PTGS2PTGS1ROCK2GSK3BCLK4 | |
| SCHEMBL6154904 | 0.77 | PTGS2 (0.51) | PTGS2ALDH1A1KDM4EGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307106-A | IMMUNO-REGULANT EFFECT, TREATING RHEUMATOID ARTHRITIS | PFIZER INC. (US) | 1981-12-22 | — | — | US | disclosed |