Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLTP | P55058 | 3/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925087 | 0.92 | NPC1 (0.54) | PTGDR2CETPNPC1RAB9AALDH1A1 | |
| SCHEMBL27925165 | 0.89 | CETP (0.50) | PTGDR2CETPNPC1RAB9AALDH1A1 | |
| SCHEMBL28020949 | 0.83 | NPC1 (0.52) | PTGDR2CETPNPC1RAB9AALDH1A1 | |
| SCHEMBL1305146 | 0.82 | PLTP (0.72) | PLTPPTGDR2NPC1RAB9AMAPT | |
| SCHEMBL27907145 | 0.81 | PTGDR2 (0.47) | PTGDR2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL11368657 | 0.81 | PTGS2 (0.65) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL27907150 | 0.80 | ADORA2A (0.50) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL27907147 | 0.80 | RAB9A (0.54) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL1303816 | 0.77 | ADORA1 (0.66) | PLTPPTGDR2NPC1RAB9AALDH1A1 | |
| SCHEMBL1304427 | 0.77 | ADORA1 (0.65) | PLTPPTGDR2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159695-B | HIV can be suppressed to copy and to effective thiazole compound of resistance HIV virus strain and its production and use | CAPITAL NORMAL UNIVERSITY (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | claimed |
| CN-103159695-B | HIV can be suppressed to copy and to effective thiazole compound of resistance HIV virus strain and its production and use | CAPITAL NORMAL UNIVERSITY (CN) | 2015-08-12 | — | — | CN | disclosed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | disclosed |