Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 5/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113364 | 0.79 | KDM4E (0.75) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL11364196 | 0.72 | KCNJ11 (0.57) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL7117140 | 0.71 | KCNJ11 (0.76) | SMN1; SMN2KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL14593291 | 0.71 | KDM4E (0.66) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL17287118 | 0.70 | SMN1; SMN2 (0.43) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL17711245 | 0.69 | KDM4E (0.54) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL1873962 | 0.69 | ALDH1A1 (0.50) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL7032993 | 0.68 | LMNA (0.50) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL2582219 | 0.68 | MEN1 (0.52) | KDM4EMEN1MAPTKMT2ALMNA | |
| SCHEMBL11365242 | 0.67 | ALOX15 (0.45) | KDM4EMEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283537-A | Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation | POLAROID CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4259493-A | INDICATOR DYES OR PHOTOGRAPHIC LIGHT-SCREENING DYES | POLAROID CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |