Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.52 |
| ▸ | ACHE | P22303 | 13/20 | 0.52 |
| ▸ | BCHE | P06276 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375582 | 0.80 | BACE1 (0.49) | BACE1ACHEBCHEMEN1ALDH1A1 | |
| SCHEMBL5850067 | 0.78 | BACE1 (0.82) | BACE1ACHEBCHE | |
| SCHEMBL5850070 | 0.78 | BACE1 (0.82) | BACE1ACHEBCHE | |
| SCHEMBL11376120 | 0.77 | BACE1 (0.66) | BACE1ACHEBCHE | |
| SCHEMBL11372233 | 0.75 | BACE1 (0.65) | BACE1ACHEBCHEHTR7 | |
| SCHEMBL11378628 | 0.74 | ACHE (0.52) | BACE1ACHEBCHEMEN1KMT2A | |
| SCHEMBL11371772 | 0.73 | ACHE (0.56) | ACHEALDH1A1KMT2AHTR7 | |
| SCHEMBL6791318 | 0.70 | HTR7 (0.59) | ACHEMEN1ALDH1A1KMT2AHTR7 | |
| SCHEMBL11381210 | 0.70 | BACE1 (0.59) | BACE1ACHEBCHE | |
| SCHEMBL11381943 | 0.70 | KMT2A (0.49) | BACE1ACHEBCHEMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |