Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491500 | 0.87 | KMT2A (0.49) | HTR7KMT2ACYP2A13ALDH1A1LMNA | |
| SCHEMBL2491547 | 0.85 | ALDH1A1 (0.49) | HTR7KMT2ACYP2A13ALDH1A1LMNA | |
| SCHEMBL329437 | 0.85 | KMT2A (0.72) | KMT2ACYP2A13ALDH1A1LMNAACHE | |
| SCHEMBL1111691 | 0.85 | HTR7 (0.56) | HTR7KMT2ACYP2A13ALDH1A1LMNA | |
| SCHEMBL1882777 | 0.83 | KMT2A (0.70) | KMT2ACYP2A13ALDH1A1LMNAACHE | |
| SCHEMBL1164984 | 0.83 | KMT2A (0.70) | KMT2ACYP2A13ALDH1A1LMNAACHE | |
| SCHEMBL11371772 | 0.82 | ACHE (0.56) | HTR7KMT2ACYP2A13ALDH1A1LMNA | |
| SCHEMBL11849036 | 0.81 | ALDH1A1 (0.55) | HTR7KMT2AALDH1A1LMNAHRH3 | |
| Hydrochloric Acid SCHEMBL23850614 | 0.79 | LMNA (0.71) | KMT2ACYP2A13ALDH1A1LMNAACHE | |
| SCHEMBL12856255 | 0.79 | KMT2A (0.76) | KMT2ACYP2A13ALDH1A1LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821964-B2 | FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH MONOCYTE ACCUMULATION, LYMPHOCYTE ACCUMULATION OR LEUCOCYTE ACCUMULATION | PFIZER INC | 2004-11-23 | — | — | US | disclosed |