Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.52 |
| ▸ | BACE1 | P56817 | 13/20 | 0.52 |
| ▸ | BCHE | P06276 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371722 | 0.80 | ACHE (0.50) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL13800326 | 0.79 | ACHE (0.71) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11371638 | 0.76 | ACHE (0.68) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11374561 | 0.74 | ACHE (0.67) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11371346 | 0.74 | BACE1 (0.52) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL11371772 | 0.73 | ACHE (0.56) | ACHEKMT2AHTR7 | |
| SCHEMBL15026727 | 0.73 | ACHE (0.71) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL18640249 | 0.72 | CARM1 (0.55) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL13321378 | 0.72 | KDM4E (0.53) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL6791318 | 0.71 | HTR7 (0.59) | ACHEMEN1KMT2APOLBHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |