Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30553151 | 0.81 | ALOX15 (0.44) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL24131432 | 0.79 | PGR (0.45) | HPGDALOX15CYP3A4KMT2AALOX12 | |
| SCHEMBL818330 | 0.78 | HSD17B10 (0.48) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL16797685 | 0.78 | CA1 (0.43) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL11373504 | 0.76 | BCL2 (0.42) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL1348538 | 0.76 | KCNH2 (0.49) | HSP90AA1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL11317922 | 0.75 | HSD17B10 (0.50) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL768507 | 0.75 | ALDH1A1 (0.61) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL18470537 | 0.74 | MEN1 (0.41) | HSP90AA1HPGDALOX15HIF1ACYP3A4 | |
| SCHEMBL2437476 | 0.73 | ALOX15 (0.44) | HSP90AA1HPGDALOX15HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |