Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381909 | 0.91 | ALDH1A1 (0.44) | RAB9ANPC1MAPK1TP53ALDH1A1 | |
| SCHEMBL7628324 | 0.89 | PCTP (0.42) | RAB9ANPC1MAPK1TP53ALDH1A1 | |
| SCHEMBL11524059 | 0.88 | TRPV1 (0.42) | RAB9ANPC1MAPK1TP53ALDH1A1 | |
| SCHEMBL11380577 | 0.87 | NPC1 (0.49) | RAB9ANPC1MAPK1TP53ALDH1A1 | |
| SCHEMBL11370198 | 0.86 | TRPV1 (0.45) | RAB9ANPC1MAPK1TP53ALDH1A1 | |
| SCHEMBL11522579 | 0.82 | MEN1 (0.41) | RAB9ANPC1ALDH1A1MAPTTRPV1 | |
| SCHEMBL3665409 | 0.82 | MAPT (0.38) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11371270 | 0.80 | SMO (0.47) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL11379838 | 0.80 | CNR1 (0.46) | RAB9ANPC1MAPK1ALDH1A1LMNA | |
| SCHEMBL11373545 | 0.80 | CNR1 (0.44) | RAB9ANPC1TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293552-A | Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |