Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369302 | 0.91 | MGLL (0.47) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL11375998 | 0.87 | OPRD1 (0.48) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL11377370 | 0.85 | SMN1; SMN2 (0.44) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL8713092 | 0.84 | OPRM1 (0.63) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL2306320 | 0.82 | L3MBTL3 (0.61) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL11381417 | 0.82 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1L3MBTL1 | |
| SCHEMBL6979086 | 0.81 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| Hydrochloric Acid SCHEMBL6984780 | 0.81 | L3MBTL3 (0.59) | OPRM1OPRD1OPRK1OPRL1L3MBTL1 | |
| SCHEMBL11375006 | 0.79 | OPRD1 (0.49) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL11384079 | 0.79 | ALDH1A1 (0.55) | OPRM1OPRD1OPRK1OPRL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |