Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | MAP2 | P11137 | 1/20 | 0.38 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375677 | 0.88 | PDE5A (0.54) | PDE5AALOX15HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL11374823 | 0.88 | L3MBTL1 (0.49) | PDE5AL3MBTL1CHEK2MEN1KMT2A | |
| SCHEMBL11376529 | 0.82 | PDE5A (0.48) | PDE5ARAB9AL3MBTL1NPC1TP53 | |
| SCHEMBL11380795 | 0.80 | PDE5A (0.55) | PDE5AALOX15HSD17B10ABL1GUSB | |
| SCHEMBL11377859 | 0.78 | GUSB (0.51) | PDE5AHSD17B10RAB9AL3MBTL1NPC1 | |
| SCHEMBL11374270 | 0.76 | ALDH1A1 (0.55) | PDE5AALOX15HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL11559725 | 0.76 | TP53 (0.44) | PDE5AHSD17B10TP53POLBMAPT | |
| SCHEMBL11391684 | 0.75 | PDE5A (0.41) | PDE5AHSD17B10RAB9AL3MBTL1NPC1 | |
| SCHEMBL11390124 | 0.75 | PDE5A (0.41) | PDE5AHSD17B10RAB9AL3MBTL1NPC1 | |
| SCHEMBL11382413 | 0.75 | GUSB (0.59) | POLBMEN1KMT2AGUSBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |