Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380547 | 0.91 | MGLL (0.48) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL11374443 | 0.89 | GUSB (0.53) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL11391684 | 0.88 | PDE5A (0.41) | MEN1KMT2APOLBGUSBKDM4E | |
| SCHEMBL11382413 | 0.86 | GUSB (0.59) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL11381831 | 0.85 | PDE5A (0.46) | POLBTSHRGUSBKDM4EALDH1A1 | |
| SCHEMBL11375670 | 0.82 | GUSB (0.56) | POLBTSHRSMN1; SMN2GUSBESR1 | |
| SCHEMBL11390124 | 0.81 | PDE5A (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL11549248 | 0.81 | GUSB (0.56) | MEN1KMT2APOLBTSHRSMN1; SMN2 | |
| SCHEMBL11375402 | 0.81 | AMY1A (0.50) | POLBGUSBHTTMAPTTP53 | |
| SCHEMBL11379676 | 0.80 | GUSB (0.51) | MEN1KMT2APOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |