Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 4/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377089 | 0.91 | MEN1 (0.46) | MGLLGUSBCYP1A1CYP1B1POLB | |
| SCHEMBL11375670 | 0.89 | GUSB (0.56) | GUSBPOLBTSHRSMN1; SMN2MAPT | |
| SCHEMBL11377673 | 0.88 | ALDH1A1 (0.57) | MGLLGUSBPOLBMEN1KMT2A | |
| SCHEMBL11390124 | 0.88 | PDE5A (0.41) | MGLLPOLBMEN1KMT2AMAPT | |
| SCHEMBL11383907 | 0.88 | PDE4A (0.42) | MGLLPOLBMEN1KMT2AMAPT | |
| SCHEMBL11375402 | 0.88 | AMY1A (0.50) | GUSBCYP1A1CYP1B1POLBMAPT | |
| SCHEMBL11382413 | 0.86 | GUSB (0.59) | GUSBCYP1A1CYP1B1POLBMEN1 | |
| SCHEMBL11375179 | 0.85 | PDE5A (0.45) | GUSBPOLBMAPTTP53TDP1 | |
| SCHEMBL11552075 | 0.85 | GUSB (0.47) | GUSBCYP1A1CYP1B1POLBMEN1 | |
| SCHEMBL11389001 | 0.84 | PKM (0.46) | GUSBCYP1A1CYP1B1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |