Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 3/20 | 0.51 |
| ▸ | PDE5A | O76074 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375677 | 0.89 | PDE5A (0.54) | GUSBPDE5APOLBNPC1TP53 | |
| SCHEMBL11384695 | 0.85 | GUSB (0.71) | GUSBPDE5APOLBNPC1TP53 | |
| SCHEMBL11378049 | 0.84 | GUSB (0.55) | GUSBPDE5APOLBNPC1TP53 | |
| SCHEMBL11382413 | 0.84 | GUSB (0.59) | GUSBPOLBKDM4EHPGDTNKS | |
| SCHEMBL11383679 | 0.83 | PDE5A (0.66) | GUSBPDE5AMAPTKDM4EHPGD | |
| SCHEMBL11380722 | 0.82 | PDE5A (0.59) | GUSBPDE5APOLBNPC1TP53 | |
| SCHEMBL11374270 | 0.82 | ALDH1A1 (0.55) | GUSBPDE5APOLBTP53MAPT | |
| SCHEMBL11375259 | 0.82 | PDE5A (0.58) | GUSBPDE5AMAPTKDM4EHPGD | |
| SCHEMBL11380795 | 0.81 | PDE5A (0.55) | GUSBPDE5AKDM4EHPGDTNKS | |
| SCHEMBL11374673 | 0.81 | GUSB (0.58) | GUSBPDE5APOLBNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |