Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.55 |
| ▸ | GUSB | P08236 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375677 | 0.91 | PDE5A (0.54) | PDE5AGUSBALOX15HSD17B10KDM4E | |
| SCHEMBL11374270 | 0.86 | ALDH1A1 (0.55) | PDE5AGUSBALOX15HSD17B10KDM4E | |
| SCHEMBL10205334 | 0.81 | GUSB (0.68) | PDE5AGUSBKDM4EHPGDTNKS | |
| SCHEMBL11377859 | 0.81 | GUSB (0.51) | PDE5AGUSBHSD17B10KDM4EHPGD | |
| SCHEMBL11559725 | 0.80 | TP53 (0.44) | PDE5AGUSBHSD17B10KDM4EHPGD | |
| SCHEMBL11383000 | 0.80 | PDE5A (0.44) | PDE5AGUSBALOX15HSD17B10ABL1 | |
| SCHEMBL11382413 | 0.79 | GUSB (0.59) | GUSBKDM4EHPGDTNKS | |
| SCHEMBL11390124 | 0.79 | PDE5A (0.41) | PDE5AHSD17B10KDM4EHPGDTNKS | |
| SCHEMBL11391684 | 0.79 | PDE5A (0.41) | PDE5AGUSBHSD17B10KDM4EHPGD | |
| SCHEMBL11554463 | 0.78 | GUSB (0.51) | PDE5AGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |