Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GUSB | P08236 | 2/20 | 0.52 |
| ▸ | PDE5A | O76074 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375840 | 0.89 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10GUSB | |
| SCHEMBL11375677 | 0.88 | PDE5A (0.54) | KDM4EHPGDHSD17B10GUSBPDE5A | |
| SCHEMBL11380795 | 0.86 | PDE5A (0.55) | KDM4EHPGDHSD17B10GUSBPDE5A | |
| SCHEMBL11384809 | 0.85 | GUSB (0.56) | ALDH1A1KDM4EHPGDHSD17B10GUSB | |
| SCHEMBL11378233 | 0.85 | GUSB (0.55) | ALDH1A1KDM4EHPGDHSD17B10GUSB | |
| SCHEMBL11377859 | 0.82 | GUSB (0.51) | ALDH1A1KDM4EHPGDHSD17B10GUSB | |
| SCHEMBL11553644 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10GUSB | |
| SCHEMBL11384695 | 0.79 | GUSB (0.71) | GUSBPDE5AMAPTTP53MEN1 | |
| SCHEMBL10205334 | 0.78 | GUSB (0.68) | KDM4EHPGDGUSBPDE5ARAB9A | |
| SCHEMBL11389503 | 0.78 | TNKS (0.58) | GUSBMEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |