Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12987281 | 0.85 | MAOB (0.71) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL19157998 | 0.81 | MAOB (0.61) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL42302 | 0.81 | MAOB (1.00) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL4602806 | 0.81 | MAOB (0.70) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL16795721 | 0.80 | NR4A1 (0.62) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL1069504 | 0.79 | MAOB (0.63) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL10974421 | 0.79 | MAOA (0.50) | MAOBEGFRSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15596323 | 0.78 | MAOB (0.66) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL978502 | 0.78 | RAB9A (0.71) | MAOBNR4A1NR4A2NR4A3PARP10 | |
| SCHEMBL27875463 | 0.78 | NR4A1 (0.70) | MAOBNR4A1NR4A2NR4A3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023385-A1 | Ethanamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-02-04 | — | — | EP | disclosed |