Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380592 | 0.78 | LMNA (0.47) | PTGS2PTGS1BRD4JAK2GHSR | |
| SCHEMBL11376209 | 0.77 | LMNA (0.46) | PTGS2PTGS1BRD4JAK2GHSR | |
| SCHEMBL11378345 | 0.77 | LMNA (0.46) | PTGS2PTGS1BRD4JAK2GHSR | |
| SCHEMBL11182644 | 0.76 | PTGS1 (0.41) | PTGS2PTGS1CA2CA1 | |
| SCHEMBL11467996 | 0.75 | KMT2A (0.44) | PTGS2PTGS1BRD4 | |
| SCHEMBL11191391 | 0.73 | KMT2A (0.53) | GHSR | |
| SCHEMBL11459823 | 0.72 | KMT2A (0.49) | — | |
| SCHEMBL26418314 | 0.64 | MAPT (0.43) | PTGS2PTGS1CA2CA1 | |
| SCHEMBL11489234 | 0.64 | HTR7 (0.34) | PTGS2PTGS1BRD4CA2CA1 | |
| SCHEMBL122373 | 0.63 | MAPK1 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011693-A1 | N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |