Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.38 |
| ▸ | ESR1 | P03372 | 8/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375905 | 0.81 | ALDH1A1 (0.48) | MAPTKMT2APTGS2ALDH1A1PKM | |
| SCHEMBL12362850 | 0.73 | ENPP2 (0.41) | ENPP2ESR2ESR1MELKFGFR1 | |
| SCHEMBL11380491 | 0.73 | MAPT (0.41) | ENPP2ESR2ESR1MAPTFGFR1 | |
| SCHEMBL27348659 | 0.71 | LMNA (0.56) | ENPP2MAPTKMT2APTGS2ALDH1A1 | |
| SCHEMBL11375286 | 0.69 | ESR1 (0.41) | ENPP2ESR2ESR1MAPTFGFR1 | |
| SCHEMBL1047014 | 0.66 | GAA (0.36) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11072010 | 0.66 | ALDH1A1 (0.45) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11973622 | 0.63 | MAPK1 (0.35) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| Hydroquinone SCHEMBL28903112 | 0.61 | ENPP2 (0.65) | ENPP2ESR2ESR1MAPTMEN1 | |
| Hydroquinone SCHEMBL575590 | 0.61 | ENPP2 (0.65) | ENPP2ESR2ESR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268680-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-05-19 | — | — | US | disclosed |
| US-4244964-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-01-13 | — | — | US | disclosed |
| US-4232034-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-11-04 | — | — | US | disclosed |
| US-4229581-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-10-21 | — | — | US | disclosed |
| US-4229460-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-10-21 | — | — | US | disclosed |
| US-4160841-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1979-07-10 | — | — | US | disclosed |