SCHEMBL1047014

SCHEMBL1047014

Cn1cnnc1S(C)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 8/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
RAB9A P51151 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MITF O75030 1/20 0.33
ALPL P05186 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
NPC1 O15118 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25280972 0.80 KMT2A (0.32) GAAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL23718250 0.80 ALDH1A1 (0.33) GAAKMT2AMEN1ALDH1A1MAPT
SCHEMBL14486996 0.77 GAA (0.36) GAAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL3099330 0.72 LOXL2 (0.33) GAAKMT2AMEN1ALDH1A1MAPT
SCHEMBL11380717 0.66 ENPP2 (0.41) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL12798233 0.60 MAPT (0.34) GAAKMT2AALDH1A1MAPTRAB9A
SCHEMBL12902951 0.60 MAPT (0.43) KMT2AALDH1A1MAPTRAB9AHTT
SCHEMBL31286470 0.59 ALDH1A1 (0.35) GAAKMT2AALDH1A1MAPTKDM4E
SCHEMBL10448183 0.59 ALDH1A1 (0.41) GAAKMT2AMEN1ALDH1A1MAPT
SCHEMBL13006988 0.59 IDO1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118755533-A Long-life low-corrosion chip photoresist cleaning solution and preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-11 CN claimed
CN-118755533-A Long-life low-corrosion chip photoresist cleaning solution and preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-11 CN disclosed
US-20220267281-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2022-08-25 US disclosed
US-20220267281-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2022-08-25 US disclosed
EP-3983406-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF Ontario Institute for Cancer Research (OICR) (CA) 2022-04-20 EP disclosed
WO-2020248065-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2020-12-17 WO disclosed
WO-2020248065-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) 2020-12-17 WO disclosed
US-20160130454-A1 INK COMPOSITION SEIKO EPSON CORPORATION (JP) 2016-05-12 US disclosed
EP-2778201-B1 COLOURED COMPOSITION AND INK FOR INKJET RECORDING FUJIFILM CORP (JP) 2016-04-06 EP disclosed
EP-2921531-A1 COLORING COMPOSITION, INK JET RECORDING INK, INK JET RECORDING METHOD, INK JET PRINTER CARTRIDGE, AND INK JET RECORDING MATERIAL Fujifilm Corporation (JP) 2015-09-23 EP disclosed
EP-2921530-A1 COLORING COMPOSITION, INK JET RECORDING INK USING COLORING COMPOSITION, INK JET RECORDING METHOD USING INK JET RECORDING INK, INK CARTRIDGE, AND INK JET RECORDING MATERIAL FUJIFILM Corporation (JP) 2015-09-23 EP disclosed
CN-102007120-B Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG (DE) 2015-09-16 CN disclosed
US-8981111-B2 Fungicide hydroximoyl-heterocycles derivatives BAYER CROPSCIENCE AG (DE) 2015-03-17 US disclosed
US-20140238264-A1 COLORING COMPOSITION AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
CN-102007120-A Fungicide hydroxyimino-heterocyclic derivatives BAYER CROPSCIENCE AG 2011-04-06 CN disclosed
US-20110034445-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-02-10 US disclosed
EP-2271641-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES Bayer CropScience AG (DE) 2011-01-12 EP disclosed
WO-2009130193-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES BAYER CROPSCIENCE SA (FR) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034445-A1 FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES HAAO, HPD, CYP51A1 GAA 696/4885KMT2A 766/4885MEN1 998/4885
US-20220267281-A1 UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF AADAC, ACSL3, ACSL1 GAA 1198/4885KMT2A 2302/4885MEN1 2476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.