Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891245 | 1.00 | RET (0.40) | RETKDRSTK17BCYP19A1MAOB | |
| SCHEMBL8030421 | 0.79 | ALDH1A1 (0.34) | CYP19A1MAOBADORA3ARKDM4E | |
| SCHEMBL8513596 | 0.77 | RET (0.36) | RETKDRSTK17BCYP19A1MAOB | |
| SCHEMBL15275913 | 0.77 | S100A4 (0.35) | CYP19A1MEN1KMT2A | |
| SCHEMBL22146506 | 0.76 | MAOB (0.38) | RETKDRSTK17BCYP19A1MAOB | |
| SCHEMBL24678396 | 0.75 | SETD7 (0.34) | KDM4E | |
| SCHEMBL278741 | 0.74 | KMT2A (0.50) | KDM4EHSD17B10MEN1POLBKMT2A | |
| SCHEMBL29689764 | 0.74 | KMT2A (0.50) | KDM4EHSD17B10MEN1POLBKMT2A | |
| SCHEMBL450880 | 0.73 | CHRM1 (0.38) | MAOB | |
| SCHEMBL9949003 | 0.73 | ALDH1A1 (0.46) | KDM4EHSD17B10MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190070-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME | LG CHEM, LTD. (KR) | 2020-06-18 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-4290954-A | ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS, ANALGESICS, ANTIINFLAMMATORY AGENTS | KOWA COMPANY LIMITED (JP) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190070-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME | CRY1, CRY2, CYP1A1 | RET 2371/4885KDR 2178/4885STK17B 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.