Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.48 |
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
| ▸ | PDE6D | O43924 | 2/20 | 0.44 |
| ▸ | PDE6A | P16499 | 2/20 | 0.44 |
| ▸ | PDE6G | P18545 | 2/20 | 0.44 |
| ▸ | PDE6B | P35913 | 2/20 | 0.44 |
| ▸ | PDE6C | P51160 | 2/20 | 0.44 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381837 | 0.91 | PDE5A (0.53) | PDE5AWDR5PDE6C | |
| SCHEMBL11384758 | 0.89 | LMNA (0.49) | PDE5AWDR5 | |
| SCHEMBL11386259 | 0.88 | PDE5A (0.53) | PDE5AWDR5PDE6DPDE6APDE6G | |
| SCHEMBL11381526 | 0.88 | NPSR1 (0.50) | — | |
| SCHEMBL11374918 | 0.87 | NPSR1 (0.42) | PDE5A | |
| SCHEMBL11375179 | 0.83 | PDE5A (0.45) | PDE5A | |
| SCHEMBL11381858 | 0.82 | ALDH1A1 (0.48) | PDE5A | |
| SCHEMBL11549969 | 0.82 | GUSB (0.49) | PDE5A | |
| SCHEMBL11382937 | 0.81 | PDE5A (0.44) | PDE5APDE6C | |
| SCHEMBL11380722 | 0.81 | PDE5A (0.59) | PDE5APDE6DPDE6APDE6GPDE6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |